Niox Flex a Nitric Oxide Monitoring System

Aerocrine is proud to announce the introduction of NIOX Flex!

NIOX Flex is the successor of NIOX, the first tailor-made Nitric Oxide Monitoring System. NIOX Flex measures NO in exhaled air according to ATS/ERS FE_NO guidelines and is cleared by FDA, for routine clinical use in asthma patients (1), (2), (3).

NIOX Flex measures FE_NO, fractional exhaled nitric oxide, to evaluate responsiveness of anti-inflammatory therapy in asthma patients. Put simply, NIOX Flex lets you see more than your asthma patients can tell you.

NIOX Flex uses the high sensitivity and specificity of a chemiluminescence gas analyzer, together with integrated software, to accurately measure NO molecules at very low concentrations.

Despite the advanced technology employed, the device is very easy to use and is suitable not only for adults, but also for children age 4 and up.

Intended Use

NIOX Flex measures Nitric Oxide (NO) in human breath. Nitric Oxide is frequently increased in some inflammatory processes such as asthma. The fractional NO concentration in expired breath (FE_NO) can be measured by NIOX Flex with assurance that such measurements are repeatable and according to guidelines for NO measurement established by the American Thoracic Society.

Measurement of FE_NO by NIOX Flex is a quantitative, non-invasive, simple and safe method to measure the decrease in FE_NO concentration in asthma patients that often occurs after treatment with anti-inflammatory pharmacological therapy, as an indication of the therapeutic effect in patients with elevated FE_NO levels. NIOX Flex is suitable for children, approximately 4–17 years, and adults 18 years and older.

FE_NO measurements provide the physician with means of evaluating an asthma patient’s response to anti-inflammatory therapy, as an adjunct to established clinical and laboratory assessments in asthma. NIOX Flex should only be used by trained physicians, nurses, respiratory therapists and laboratory technicians. NIOX Flex cannot be used with infants or by children approximately under the age of 4, as measurement requires patient cooperation. NIOX Flex should not be used in critical care, emergency care or in anesthesiology.

Do you already have a NIOX system? Rebuild your NIOX to a NIOX Flex!

Aerocrine is a clinically based medical technology corporation dedicated to improved asthma management and care. The NIOX^® product range is tailored for rapid, non-invasive measurement of exhaled Nitric Oxide to determine the inflammatory status in the airways and may play a critical role for optimized asthma care and disease control.

Aerocrine is located in Sweden with wholly owned subsidiaries in the US, UK and Germany.

More information about Aerocrine and nitric oxide as an inflammatory marker.